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Earlier stages of kidney disease can often be detected only through laboratory testing. Measurement of serum creatinine (with estimation of GFR) and urinary albumin can identify patients with reduced kidney function. Screening asymptomatic individuals at increased risk could allow earlier detection of chronic kidney disease.
Therapeutic interventions at earlier stages of chronic kidney disease are effective in slowing the progression of chronic kidney disease. The major therapeutic strategies that have been tested include strict blood glucose control in diabetes, strict blood pressure control, angiotensin-converting enzyme (ACE) inhibitors and angiotensin-receptor blockers, and dietary protein restriction.